From Wikipedia,

Notable American lesbians

Tammy Baldwin became the first open lesbian ever elected to Congress in 1998.[136][137] In 2012 she became the first openly lesbian or gay senator in American history.[308]

Ann Bannon, author who, from 1957 to 1962, wrote six lesbian pulp fiction novels known as The Beebo Brinker Chronicles. The books' enduring popularity and impact on lesbian identity earned her the title "Queen of Lesbian Pulp Fiction".[325]

Michelle Cliff, poet.

Ellen DeGeneres came out as a lesbian in 1997, one of the first celebrities to do so, and later that year her character Ellen Morgan came out as a lesbian on the TV show "Ellen", making her the first openly lesbian actress to play an openly lesbian character on television.[145][146] In 2007, she became the first open lesbian to host the Academy Awards.[326] She is currently a talk show host, for which she has won Emmys.[327]

Lea DeLaria, entertainer.

Melissa Etheridge, a multiplatinum-selling singer, came out as a lesbian in 1993.[139][140] In 1995 she won a Grammy and in 2007 she won an Academy Award for Best Song.[328]

Jane Lynch, an Emmy-winning actress best known for her role on the TV series Glee, is openly lesbian.[329]

Rachel Maddow became the first openly lesbian or gay American to win an international Rhodes scholarship in 1995, and the first openly lesbian or gay anchor of a major prime-time news program in America in 2008,[330] when she began hosting The Rachel Maddow Show on MSNBC.

Kate McKinnon, comedian and actress, known for Saturday Night Live and Ghostbusters (2016 film). She became Saturday Night Live's first openly lesbian cast member in 2012. In 2016, she won both an Emmy award and a Critics' Choice Award for her work on Saturday Night Live.

Carole Migden, politician.

Elaine Noble, politician.

Suze Orman, financial consultant.[331]

Rosie O'Donnell, Actress and talk show host.

Adrienne Rich, poet.

Wanda Sykes, a writer, comedian, actress, and voice artist, came out as a lesbian in 2008. She is well known for her role as Barbara Baran on The New Adventures of Old Christine and for her appearances on HBO's Curb Your Enthusiasm.